منابع مشابه
Immunogenicity and Efficacy of Different Haemophilus influenzae type b Vaccines
Haemophilus influenzae, a major cause of meningitis in young children leading to death and other neurological sequelae. The disease leaves 15 to 35% of the survivors with permanent disabilities, such as, mental retardation or deafness. Despite the availability of new and more powerful antibiotics children with Hib meningitis still suffer from high mortality or morbidity. The emergence of multir...
متن کاملReflections on the efficacy of pertussis vaccines.
The literature on the protection imparted by conventional whole-cell pertussis vaccines was reviewed, and the extent to which the great variation in estimates of vaccine efficacy is attributable to methodologic problems in study design and analysis or to biologic features of the natural history of pertussis was explored. The protection against disease imparted by pertussis vaccines may be great...
متن کاملMeningococcal conjugate vaccines: efficacy and new combinations.
OBJECTIVE Meningococcal disease continues to be a serious public health concern, being associated with high morbidity and mortality rates worldwide, particularly in Brazil. In addition to discussing recent changes in the global epidemiology of meningococcal disease, we also analyze the development and impact of new conjugate vaccines on the prevention of meningococcal disease, with emphasis on ...
متن کاملEfficacy of pertussis vaccines: a brighter horizon.
A study of pertussis infections in 186 children under 11 years of age in the Manchester region during 1969-71 suggests that recently-manufactured vaccines have been more effective than those made before 1967. The earlier vaccines were effective mainly against the serotypes of Bordetella pertussis possessing antigen 2, while those made from 1967 are more nearly equal in their effectiveness again...
متن کاملThe Efficacy of Experimental Angara Disease Vaccines
Formalinized aqua based liver organ vaccines for Angara disease (AD)/hydropericardium-hepatitis syndrome (HHS) are effective for the control of the disease. The experimental formalinized 10, 7.5 and 5% liver organ vaccines showed significant differences in efficacy from 2.5 and 1% liver organ vaccines. However, 10, 7.5 and 5% liver organ vaccines differed non significantly from one another. The...
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ژورنال
عنوان ژورنال: BMJ
سال: 1995
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.311.7001.388